[Todos] Fwd: Seminario/Charla del Prof Dr. Sergey Krylov

[Asistentes de Secretaria de Fisica]

-------- Mensaje original -------- 

 		ASUNTO:
 		Seminario/Charla del Prof Dr. Sergey Krylov

 		FECHA:
 		2016-12-06 13:42

 		REMITENTE:
 		Información Exactas <info at exactas.unlp.edu.ar>

 		DESTINATARIO:
 		"secre, secre" <secre at mate.unlp.edu.ar>, "secre, secre"
<secre at biol.unlp.edu.ar>, "secre, secre" <secre at quimica.unlp.edu.ar>,
"secre, secre" <secre at fisica.unlp.edu.ar>

Estimados,

El próximo lunes 12 a las 14:30 en el aula del Consejo nos dará una
charla el Dr. Sergey Krylov, (Department of Chemistry and Centre for
Research on Biomolecular Interactions, York University, Toronto, Canada)
quien estará también unos días de visita en los laboratorios del LIDMA. 


El Dr. Krylov trabaja en desarrollo de métodos de análisis y de
tecnologías (plataformas) aplicadas al estudio de biomoléculas,
"-omicas" (genómica/ proteómica/metabolómica, etc.) y de interacciones
biomoleculares. Se especializa en métodos cinéticos de electroforesis y
cromatografía de líquidos, acoplados a detectores de alta "sensibilidad"
(espectrometría de masas, fluorescencia, etc..). Tiene más de 150
publicaciones en revistas de máximo impacto
(https://www.scopus.com/authid/detail.uri?authorId=7005051872) y
convenios con empresas como Sciex.

La charla será en idioma inglés y tratará sobre las diversas líneas de
desarrollo tecnológico / plataformas en las que está trabajando
actualmente su grupo:

_"__KINETIC SEPARATION: A CONCEPTUAL PLATFORM FOR DEVELOPMENT OF
HOMOGENEOUS KINETIC AFFINITY METHODS__"_

_"SEPARACIÓN CINÉTICA: PLATAFORMA CONCEPTUAL PARA EL DESARROLLO DE
MÉTODOS DE AFINIDAD CINÉTICA HOMOGÉNEA"_

Se adjunta el texto del abstract de la charla. 

Para mayor información, contactarse con el Dr. Leonardo Gagliardi (
leogagliardi at quimica.unlp.edu.ar )

-----------------------------------------------------------------------------------------------------------------------------------
Title: Kinetic Separation: A Conceptual Platform for Development of
Homogeneous Kinetic Affinity Methods 

Abstract: Non-covalent binding of biological molecules controls cellular
regulation, it is also pivotal to action of modern drugs and molecular
diagnostics of diseases. Therefore, understanding molecular mechanisms
of biological processes as well as the development of drugs and design
of diagnostic systems require affinity methods suitable for three types
of applications: (i) kinetic studies of affinity interactions, (ii)
selection of affinity ligands from combinatorial libraries, and (iii)
the use of affinity ligands as diagnostic probes in molecular
diagnostics of diseases. Our answer to this challenge is Kinetic
Separation - a conceptual platform for the development of homogeneous
kinetic affinity methods suitable for all three applications.
One-dimensional (column) separation of any nature, e.g. electrophoresis,
gel-filtration, thermophoresis, sedimentation, that can segregate
affinity complexes from the unbound interactants, can be used as the
basis for kinetic separation. A variety of different detection methods
can be employed in kinetic separation including fluorescence and
mass-spectrometry. In this lecture, I will explain the physical
principles underlying kinetic separation and discuss two practical
implementations of kinetic separation for (i) selection, kinetic
characterization, and analytical use of DNA aptamers by means of Kinetic
Capillary Electrophoresis and (ii) studying kinetics of reversible
protein-drug binding by means of Kinetic Size-Exclusion Chromatography. 

-------------------------

 		 [1]

El software de antivirus Avast ha analizado este correo electrónico en
busca de virus. 
www.avast.com [1] 

 

Links:
------
[1]
https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=emailclient
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://mail.fisica.unlp.edu.ar/pipermail/todos/attachments/20161206/d8236bb6/attachment.html>