[Todos] Fwd: RECORDATORIO Charla IFLYSIB: Martes 14/11 - 10:30 hs. Charla: Recruitment shapes the Vestigial pattern and contributes to wing growth in Drosophila

[Asistentes de Secretaria de Fisica]

-------- Mensaje original -------- 

 		ASUNTO:
 		RECORDATORIO Charla IFLYSIB: Martes 14/11 - 10:30 hs. Charla:
Recruitment shapes the Vestigial pattern and contributes to wing growth
in Drosophila

 		FECHA:
 		2017-11-13 15:06

 		REMITENTE:
 		Charlas Iflysib <charlas.iflysib at gmail.com>

 		DESTINATARIO:
 		Charlas Iflysib <charlas-iflysib at googlegroups.com>

L at s invitamos a la próxima charla del IFLYSIB a realizarse el día MARTES
14/11 a las 10:30 HS.  

En esta oportunidad, LUIS MUÑOZ NAVA del Departamento de Fisiología del
CINVESTAV (México) nos hablará sobre: 

_EL RECLUTAMIENTO LE DA FORMA AL PATRÓN DE VESTIGIAL Y CONTRIBUYE AL
CRECIMIENTO DEL ALA DE DROSOPHILA_ 

Lugar: 
IFLYSIB (Instituto de Física de Líquidos y Sistemas Biológicos)

CALLE 59, 789 ENTRE 10 Y 11 

***********************************************************
_RECRUITMENT SHAPES THE VESTIGIAL PATTERN AND CONTRIBUTES TO WING GROWTH
IN DROSOPHILA_ 

How patterns that determine cell fates get established is a fundamental
problem in developmental biology. In the developing wing of Drosophila
melanogaster, the wing fate is defined by the expression of the selector
gene vestigial (vg). The size of the Vg domain is determined by two
mechanisms. First, through the proliferation of vg-expressing cells near
the dorsal-ventral boundary of the wing disc, and second, the
propagation of the Vg pattern to neighboring cells in a process known as
recruitment. Although the molecular factors that determine the
progression of recruitment have been previously documented, little is
known about the spatio-temporal propagation and contributions of these
mechanisms to the final size of the wing. We quantitatively measured the
spatial pattern of Vg at different times during wing disc development
and show that the width of the Vg gradient increases more than what
would be expected from scaling by homogeneous tissue growth.
Interestingly, the Vg pattern also changes in shape and do this in a
very specific window of time, suggesting that the contribution of the
recruitment process to the Vg pattern is spatially and temporally
controlled. Recruitment-mutant wings are proportionally smaller compared
to control wings, suggesting that recruitmentcontributes to wing size. 

-- 

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