[Todos] Fwd: Martes 22/08 - 11:30hs - Charla: Spatial and temporal regulation of low-copy number plasmids

[Asistentes de Secretaria de Fisica]

-------- Mensaje original -------- 

 		ASUNTO:
 		Martes 22/08 - 11:30hs - Charla: Spatial and temporal regulation of
low-copy number plasmids

 		FECHA:
 		2017-08-16 15:36

 		REMITENTE:
 		Charlas Iflysib <charlas.iflysib at gmail.com>

 		DESTINATARIO:

Les invitamos a la próxima charla del Iflysib a realizarse el día MARTES
22/08 a las 11:30 HS. 

En esta oportunidad, BAPTISTE GUILHAS (Center for Structural
Biochemistry - CNRS/INSERM/UM, Montpellier, France) nos hablará (en
inglés) sobre: 

 _SPATIAL AND TEMPORAL REGULATION OF LOW-COPY NUMBER PLASMIDS_

Besides their single chromosome, bacteria carry plasmids that are small
DNA molecules replicating autonomously. For high-copy number plasmids,
random diffusion is sufficient to ensure both daughter cells inherit at
least one plasmid copy following cell division, while low-copy number
plasmids (i.e typically one or two copies per cells) encode dedicated
partition (Par) systems to actively segregate DNA and therefore to
ensure their faithful transmission. F-plasmids regulate their positions
using the highly conserved ParABS system which encodes only two
proteins, ParA and ParB, and a parS partition site. Together they must
precisely position newly replicated plasmids before the creation of the
division septum at the middle of the cell. Despite extensive studies, we
still lack an understanding of the coordination between the bacterial
cell cycle and the low-copy number plasmids segregation. Here, we
investigate their spatial and temporal regulation using fluorescence
microscopies and stochastic simulations. 

LUGAR: 

IFLYSIB (INSTITUTO DE FÍSICA DE LÍQUIDOS Y SISTEMAS BIOLÓGICOS) 

CALLE 59, 789 ENTRE 10 Y 11 
http://iflysib.unlp.edu.ar/seminarios/ [1]

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Links:
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[1] http://iflysib.unlp.edu.ar/seminarios/
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